Detalhe da pesquisa
1.
Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells.
Int J Mol Sci
; 22(6)2021 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33799598
2.
Scalable preparation and differential pharmacologic and toxicologic profiles of primaquine enantiomers.
Antimicrob Agents Chemother
; 58(8): 4737-44, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24913163
3.
The prevalence of glucose-6-phosphate dehydrogenase deficiency in Gambian school children.
Malar J
; 13: 148, 2014 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24742291
4.
G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map.
PLoS Med
; 9(11): e1001339, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23152723
5.
DFT study on the radical anions formed by primaquine and its derivatives.
Chem Res Toxicol
; 24(9): 1476-85, 2011 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21699254
6.
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.
Toxicol Appl Pharmacol
; 241(1): 14-22, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19616568
7.
Delayed Diagnosis in Army Ranger Postdeployment Primaquine-Induced Methemoglobinemia.
J Spec Oper Med
; 19(3): 14-16, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31539427
8.
Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine.
Mol Cell Biol
; 14(4): 2419-28, 1994 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-7511206
9.
Photophysical properties and photobiological behavior of amodiaquine, primaquine and chloroquine.
Photochem Photobiol
; 83(6): 1415-27, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18028216
10.
Primaquine-induced differential gene expression analysis in mice liver using DNA microarrays.
Toxicology
; 239(1-2): 96-107, 2007 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17686563
11.
Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.
Chem Biol Interact
; 255: 63-73, 2016 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26477383
12.
Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro.
J Clin Pharmacol
; 45(3): 346-51, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15703369
13.
Photooxidation products of primaquine. Structure, antimalarial activity and hemolytic effects.
FEBS Lett
; 223(1): 77-81, 1987 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-3666145
14.
Sulfur-interrupted 8-amino side chain analogues of 4-methyl-5-[m-(trifluoromethyl)phenoxy]primaquine as potential antimalarial agents.
J Med Chem
; 28(12): 1959-62, 1985 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-4068013
15.
Carrier-linked primaquine in the chemotherapy of malaria.
J Med Chem
; 29(9): 1765-9, 1986 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-3528491
16.
Discovery of a bulky 2-tert-butyl group containing primaquine analogue that exhibits potent blood-schizontocidal antimalarial activities and complete elimination of methemoglobin toxicity.
J Med Chem
; 47(2): 285-7, 2004 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14711300
17.
The disposition of free and liposomally encapsulated antimalarial primaquine in mice.
Biochem Pharmacol
; 31(21): 3501-7, 1982 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-7150371
18.
Oxidative activity of primaquine metabolites on rat erythrocytes in vitro and in vivo.
Biochem Pharmacol
; 47(2): 309-16, 1994 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-8304975
19.
Studies on the mechanisms of oxidation in the erythrocyte by metabolites of primaquine.
Biochem Pharmacol
; 37(13): 2683-90, 1988 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-2839199
20.
Methemoglobin toxicity and hematological studies on malaria anti-relapse compound CDRI 80/53 in dogs.
Am J Trop Med Hyg
; 41(6): 638-42, 1989 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-2641641